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AMOXICILLIN DRUG INFO
IMPORTANT NOTE: What should my health care professional know
before I take amoxicillin? They need to know if you have any of these
conditions:; asthma; eczema; kidney disease; leukemia; mononucleosis;
intestinal problems (especially colitis); other chronic illness;
phenylketonuria; viral infection; an unusual or allergic reaction to
amoxicillin, other penicillins, cephalosporin antibiotics, other
medicines, foods, dyes, or preservatives; breast-feeding
AMOXICILLIN - ORAL
COMMON BRAND NAME(S): Amoxil?, Trimox?, Wymox?
USES: Amoxicillin kills or stops the growth of bacteria that
cause infection. It treats many different kinds of infections of the
skin, respiratory tract, sinuses, ear, and kidney. Amoxicillin also
treats some sexually transmitted disease.
HOW TO USE: How should I take this medicine? Take amoxicillin
capsules or chewable tablets by mouth. Chew or crush the tablets, do not
swallow whole. Swallow the capsules or tablets whole with a glass of
water; take while in an upright or sitting position. You may take
amoxicillin with or without food. Follow the directions on the
prescription label. Take your doses at regular intervals. Do not take
your medicine more often than directed. Finish the full course
prescribed by your prescriber or health care professional even if you
think your condition is better. Do not stop taking except on your
prescriber's advice.
SIDE EFFECTS: What side effects may I notice from taking
amoxicillin? Side effects that you should report to your prescriber or
health care professional as soon as possible:; difficulty breathing,
wheezing; dark yellow or brown urine; dizziness; fever or chills, sore
throat; increased thirst; pain or difficulty passing urine; pain on
swallowing; redness, blistering, peeling or loosening of the skin,
including inside the mouth; seizures (convulsions); skin rash, itching;
stomach pain or cramps; swollen joints; severe or watery diarrhea;
unusual bleeding or bruising; unusual weakness or tiredness; vomiting;
yellowing of the eyes or skin Side effects that usually do not require
medical attention (report to your prescriber or health care professional
if they continue or are bothersome):; diarrhea; headache; loss of
appetite; nausea; stomach gas or heartburn
PRECAUTIONS: If you are diabetic and taking large doses of
amoxicillin, you may get a false-positive result for sugar in your urine
with certain brands of urine tests. Check with your prescriber or health
care professional before you change your diet or the dose of your
diabetic medicine. If you get severe or watery diarrhea, do not treat
yourself. Call your prescriber or health care professional for advice.
If you get a skin rash, do not treat yourself. Call your prescriber or
health care professional for advice.
DRUG INTERACTIONS: What drug(s) may interact with amoxicillin?;
allopurinol; birth control pills; methotrexate; neomycin; probenecid
OVERDOSE: If overdose is suspected, contact your local poison
control center or emergency room immediately. Symptoms of overdose may
include sluggishness, change in amount of urine, loss of consciousness,
or seizures.
NOTES: What should my health care professional know before I take
amoxicillin? They need to know if you have any of these conditions:;
asthma; eczema; kidney disease; leukemia; mononucleosis; intestinal
problems (especially colitis); other chronic illness; phenylketonuria;
viral infection; an unusual or allergic reaction to amoxicillin, other
penicillins, cephalosporin antibiotics, other medicines, foods, dyes, or
preservatives; breast-feeding
MISSED DOSE: If you miss a dose, take as soon as remembered; do
not take if it is almost time for the next dose, instead, skip the
missed dose and resume your usual dosing schedule. Do not
"double-up" the dose to catch up.
STORAGE: Store at room temperature between 15-30 degrees C (59-86
degrees F). Keep container tightly closed. Throw away any unused
medicine after the expiration date.
Formulations of AMOXIL contain amoxicillin, a
semisynthetic antibiotic, an analog
of ampicillin, with a broad spectrum
of bactericidal
activity against many gram-positive
and gram-negative
microorganisms. Chemically it is (2S,5R,6R)-6-[(R)-(-)-2-amino-2-(p-hydroxyphenyl)acetamido]-
3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
trihydrate. It may be represented structurally as:
The amoxicillin
molecular formula is C16H19N3O5S?H2O,
and the molecular weight is
419.45.
Capsules, tablets, and powder
for oral suspension
of AMOXIL are intended for oral
administration.
Capsules: Each capsule
of AMOXIL, with royal blue
opaque cap and pink opaque
body, contains 250 mg or 500 mg
amoxicillin as the
trihydrate. The cap and body
of the 250-mg capsule are
imprinted with the product
name AMOXIL and 250; the cap
and body of the 500-mg capsule
are imprinted with AMOXIL and 500. Inactive ingredients: D&C Red No.
28, FD&C Blue No. 1, FD&C Red No. 40, gelatin, magnesium
stearate, and titanium
dioxide.
Tablets: Each tablet
contains 500 mg or 875 mg
amoxicillin as the trihydrate. Each film-coated, capsule-shaped, pink tablet
is debossed with AMOXIL centered over 500 or 875, respectively. The
875-mg tablet is scored on
the reverse side. Inactive ingredients: Colloidal silicon
dioxide, crospovidone, FD&C Red No. 30 aluminum
lake, hypromellose, magnesium
stearate, microcrystalline cellulose, polyethylene
glycol, sodium starch
glycolate, and titanium
dioxide.
Chewable Tablets: Each
cherry-banana-peppermint-flavored tablet
contains 200 mg or 400 mg
amoxicillin as the
trihydrate. Each 200-mg chewable tablet
contains 0.0005 mEq (0.0107
mg) of sodium; the 400-mg chewable tablet
contains 0.0009 mEq (0.0215
mg) of sodium. The 200-mg and 400-mg pale pink round
tablets are imprinted with the product
name AMOXIL and 200 or 400 along the edge
of 1 side. Inactive ingredients: Aspartame*, crospovidone NF, FD&C
Red No. 40 aluminum lake,
flavorings, magnesium
stearate.
Why is this medication prescribed?
Amoxicillin is used to treat certain infections
caused by bacteria, such as pneumonia; bronchitis; gonorrhea; and
infections of the ears, nose, throat, urinary tract, and skin. It is
also used in combination with other medications to eliminate
H. pylori
How should this medicine be used?
Amoxicillin comes as a capsule, a tablet, a chewable
tablet, a suspension (liquid), and pediatric drops to take by mouth. It
is usually taken every 12 hours (twice a day) or every 8 hours (three
times a day) with or without food. To help you remember to take
amoxicillin, take it around the same time every day. Follow the
directions on your prescription label carefully, and ask your doctor or
pharmacist to explain any part you do not understand. Take amoxicillin
exactly as directed. Do not take more or less of it or take it more
often than prescribed by your doctor.
Shake the liquid and pediatric drops well before
each use to mix the medication evenly. Use the bottle dropper to measure
the dose of pediatric drops. The pediatric drops and liquid may be
placed on a child's tongue or added to formula, milk, fruit juice,
water, ginger ale, or other cold liquid and taken immediately.
The chewable tablets should be crushed or chewed
thoroughly before they are swallowed. The tablets and capsules should be
swallowed whole and taken with a full glass of water.
Take amoxicillin until you finish the prescription,
even if you feel better. Stopping amoxicillin too soon may cause
bacteria to become resistant to antibiotics.
Other uses for this medicine
Amoxicillin also is used sometimes to prevent
anthrax infection after exposure and to treat anthrax infection of the
skin and chlamydia infections during pregnancy. Talk with your doctor
about the possible risks of using this medication for your condition.
This medication may be prescribed for other uses;
ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking amoxicillin,
- tell your doctor and pharmacist if you are allergic to amoxicillin,
penicillin, cephalosporins, or any other medications.
- tell your doctor and pharmacist what prescription and
nonprescription medications, vitamins, nutritional supplements, and
herbal products you are taking. Be sure to mention any of the
following: chloramphenicol (Chlormycetin), other antibiotics, and
probenecid (Benemid). Your doctor may need to change the doses of
your medications or monitor you carefully for side effects.
- tell your doctor if you have or have ever had kidney disease,
allergies, asthma, hay fever, hives, or phenylketonuria.
- tell your doctor if you are pregnant, plan to become pregnant, or
are breast-feeding. If you become pregnant while taking amoxicillin,
call your doctor.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue
your normal diet.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it.
However, if it is almost time for the next dose, skip the missed dose
and continue your regular dosing schedule. Do not take a double dose to
make up for a missed one.
What side effects can this medication cause?
Amoxicillin may cause side effects. Tell your doctor
if any of these symptoms are severe or do not go away:
- upset stomach
- vomiting
- diarrhea
Some side effects can be serious. The following
symptoms are uncommon, but if you experience any of them, call your
doctor immediately:
- severe skin rash
- hives
- seizures
- yellowing of the skin or eyes
- unusual bleeding or bruising
- pale skin
- excessive tiredness
- lack of energy
Amoxicillin may cause other side effects. Call your
doctor if you have any unusual problems while taking this medication.
What storage conditions are needed for this medicine?
Keep this medication in the container it came in,
tightly closed, and out of reach of children. Store the capsules and
tablets at room temperature and away from excess heat and moisture (not
in the bathroom). Throw away any medication that is outdated or no
longer needed. The liquid medication preferably should be kept in the
refrigerator, but it may be stored at room temperature. Throw away any
unused medication after 14 days. Do not freeze. Talk to your pharmacist
about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control
center at 1-800-222-1222. If the victim has collapsed or is not
breathing, call local emergency services at 911.
What other information should I know?
Keep all appointments with your doctor and the
laboratory. Your doctor may order certain lab tests to check your body's
response to amoxicillin.
If you are diabetic, use Clinistix or TesTape (not
Clinitest) to test your urine for sugar while taking this medication.
Do not let anyone else take your medication. Your
prescription is probably not refillable. If you still have symptoms of
infection after you finish the amoxicillin, call your doctor.
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