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Drug Information: Betamethasone Topical

(bay ta meth' a sone)

Brand name(s): Alphatrex; Beta-Val; Betalene; Betatrex; Diprolene; Diprosone; Maxivate; Valisone

Why is this medication prescribed?

Betamethasone is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used?

Betamethasone comes in ointment, cream, lotion, and aerosol (spray) in various strengths for use on the skin. It is usually applied one to four times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use betamethasone exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. Do not apply it to other areas of your body or wrap or bandage the treated area unless directed to do so by your doctor.

Wash or soak the affected area thoroughly before applying the medicine, unless it irritates your skin. Then apply the ointment or cream sparingly in a thin film and rub it in gently.

To use the lotion on your scalp, part your hair, apply a small amount of the medicine on the affected area, and rub it in gently. Protect the area from washing and rubbing until the lotion dries. You may wash your hair as usual but not right after applying the medicine.

To apply an aerosol, shake well and spray on the affected area holding the container about 3 to 6 inches away. Spray for about 2 seconds to cover an area the size of your hand. Take care not to inhale the vapors. If you are spraying near your face, cover your eyes.

Avoid prolonged use on the face, in the genital and rectal areas, and in skin creases and armpits unless directed by your doctor.

If you are using betamethasone on your face, keep it out of your eyes.

If you are using betamethasone on a child's diaper area, do not use tight-fitting diapers or plastic pants. Such use may increase side effects.

Do not apply cosmetics or other skin preparations on the treated area without talking with your doctor.

If your doctor tells you to wrap or bandage the treated area, follow these instructions:

Soak the area in water or wash it well.
While the skin is moist, gently rub the medication into the affected areas.
Cover the area with plastic wrap (such as Saran Wrap or Handi-Wrap.) The plastic may be held in place with a gauze or elastic bandage or adhesive tape on the normal skin beside the treated area. (Instead of using plastic wrap, plastic gloves may be used for the hands, plastic bags for the feet, or a shower cap for the scalp.)
Carefully seal the edges of the plastic to make sure the wrap adheres closely to the skin. If the affected area is moist, you can leave the edges of the plastic wrap partly unsealed or puncture the wrap to allow excess moisture to escape.
Leave the plastic wrapping in place as long as instructed by your doctor. Usually plastic wraps are left in place not more than 12 hours each day.
Cleanse the skin and reapply the medication each time a new plastic wrapping is applied.

Call your doctor if the treated area gets worse or if burning, swelling, redness, or oozing of pus develops.

What special precautions should I follow?

Before using betamethasone,

tell your doctor and pharmacist if you are allergic to betamethasone or any other drugs.
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially cancer chemotherapy agents, other topical medications, and vitamins.
tell your doctor if you have an infection or have ever had diabetes, glaucoma, cataracts, a circulation disorder, or an immune disorder.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using betamethasone, call your doctor immediately.

What should I do if I forget a dose?

Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not apply a double dose to make up for a missed one.

What side effects can this medication cause?

Although side effects from betamethasone are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

drying or cracking of the skin
acne
itching
burning
change in skin color

If you experience any of the following symptoms, call your doctor immediately:

severe skin rash
difficulty breathing or swallowing
wheezing
skin infection (redness, swelling, or oozing pus)

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it according to the package instructions. Throw away any medication that is outdated or no longer needed. Do not use it to treat other skin conditions. Talk to your pharmacist about the proper disposal of your medication.

What other information should I know?

Keep all appointments with your doctor.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

Drug Information: Corticosteroids Medium to Very High Potency (Topical)

Brand Names

Some commonly used brand names are:

In the U.S.?

Alphatrex³
Aristocort²⁰
Aristocort A²⁰
Betatrex³
Beta-Val³
Bio-Syn⁹
Cordran¹¹
Cordran SP¹¹
Cormax⁴
Cutivate¹²
Cyclocort¹
Delta-Tritex²⁰
Dermabet³
Dermatop¹⁹
Diprolene³
Diprolene AF³
Diprosone³
Elocon¹⁸
Florone⁷
Florone E⁷
Fluocet⁹
Fluocin¹⁰
Fluonid⁹
Flurosyn⁹
Flutex²⁰
Halog¹³
Halog-E¹³
Kenac²⁰
Kenalog²⁰
Kenalog-H²⁰

Kenonel²⁰
Licon¹⁰
Lidex¹⁰
Lidex-E¹⁰
Locoid¹⁵
Luxiq³
Maxiflor⁷
Maxivate³
Olux⁴
Pandel¹⁶
Psorcon⁷
Synalar⁹
Synalar-HP⁹
Synemol⁹
Teladar³
Temovate⁴
Temovate E⁴
Temovate Scalp Application⁴
Topicort⁶
Topicort LP⁶
Triacet²⁰
Triderm²⁰
Ultravate¹⁴
Uticort³
Valisone³
Valisone Reduced Strength³
Valnac³
Vanos¹⁰
Westcort¹⁷

In Canada?

Aristocort C²⁰
Aristocort D²⁰
Aristocort R²⁰
Beben³
Betacort Scalp Lotion³
Betaderm³
Betaderm Scalp Lotion³
Betnovate³
Betnovate-?a href="#GXXg20201603">³
Celestoderm-V³
Celestoderm-V/2³
Cyclocort¹
Dermovate⁴
Dermovate Scalp Lotion⁴
Diprolene³
Diprosone³
Drenison¹¹
Ectosone Mild³
Ectosone Regular³
Ectosone Scalp Lotion³
Elocom¹⁸
Eumovate⁵
Florone⁷
Fluoderm⁹
Fluolar⁹
Fluonide⁹

Halog¹³
Kenalog²⁰
Lidemol¹⁰
Lidex¹⁰
Lyderm¹⁰
Metaderm Mild³
Metaderm Regular³
Nerisone⁸
Nerisone Oily⁸
Novobetamet³
Occulocort³
Prevex B³
Propaderm²
Synalar⁹
Synamol⁹
Topicort⁶
Topicort Mild⁶
Topilene³
Topisone³
Topsyn¹⁰
Triaderm²⁰
Trianide Mild²⁰
Trianide Regular²⁰
Valisone Scalp Lotion³
Westcort¹⁷

Note:

For quick reference, the following medium to very high potency corticosteroids are numbered to match the corresponding brand names.

Other commonly used names are: Beclometasone Fludroxycortide Ulobetasol

This information applies to the following medicines:

1. Amcinonide (am-SIN-oh-nide)

2. Beclomethasone (be-kloe-METH-a-sone)*

3. Betamethasone (bay-ta-METH-a-sone)?/A>

4. Clobetasol (kloe-BAY-ta-sol)

5. Clobetasone (kloe-BAY-ta-sone)*

6. Desoximetasone (des-ox-i-MET-a-sone)?/A>

7. Diflorasone (dye-FLOR-a-sone)

8. Diflucortolone (dye-floo-KOR-toe-lone)*

9. Fluocinolone (floo-oh-SIN-oh-lone)?/A>

10. Fluocinonide (floo-oh-SIN-oh-nide)?/A>

11. Flurandrenolide (flure-an-DREN-oh-lide)?/A>

12. Fluticasone (floo-TIK-a-sone)?/A>

13. Halcinonide (hal-SIN-oh-nide)

14. Halobetasol (hal-oh-BAY-ta-sol)?/A>

15. Hydrocortisone butyrate (hye-droe-KOR-ti-sone bue-TEAR-ate)?/A>

16. Hydrocortisone probutate (hye-droe-KOR-ti-sone proe-BYOE-tate)

17. Hydrocortisone valerate (hye-droe-KOR-ti-sone val-AIR-ate)

18. Mometasone (moe-MET-a-sone)

19. Prednicarbate (PRED-ni-kar-bate)?/A>

20. Triamcinolone (trye-am-SIN-oh-lone)

? Generic name product may be available in the U.S.

? Generic name product may be available in Canada

* Not commercially available in the U.S.

? Not commercially available in Canada

Description

Topical corticosteroids (kor-ti-ko-STER-oyds) are used to help relieve redness, swelling, itching, and discomfort of many skin problems. These medicines are like cortisone. They belong to the general family of medicines called steroids.

These corticosteroids are available only with your doctor's prescription. Topical corticosteroids are available in the following dosage forms:

Topical

Amcinonide
- Cream (U.S. and Canada)
- Lotion (U.S. and Canada)
- Ointment (U.S. and Canada)
Beclomethasone
- Cream (Canada)
- Lotion (Canada)
Betamethasone
- Cream (U.S. and Canada)
- Foam (U.S.)
- Gel (U.S. and Canada)
- Lotion (U.S. and Canada)
- Ointment (U.S. and Canada)
- Topical aerosol (U.S.)
Clobetasol
- Cream (U.S. and Canada)
- Foam (U.S.)
- Ointment (U.S. and Canada)
- Topical solution (U.S. and Canada)
Clobetasone
- Cream (Canada)
- Ointment (Canada)
Desoximetasone
- Cream (U.S. and Canada)
- Gel (U.S. and Canada)
- Ointment (U.S.)
Diflorasone
- Cream (U.S. and Canada)
- Ointment (U.S. and Canada)
Diflucortolone
- Cream (Canada)
- Ointment (Canada)
Fluocinolone
- Cream (U.S. and Canada)
- Ointment (U.S. and Canada)
- Topical solution (U.S. and Canada)
Fluocinonide
- Cream (U.S. and Canada)
- Gel (U.S. and Canada)
- Ointment (U.S. and Canada)
- Topical solution (U.S. and Canada)
Flurandrenolide
- Cream (U.S. and Canada)
- Lotion (U.S.)
- Ointment (U.S. and Canada)
- Tape (U.S. and Canada)
Fluticasone
- Cream (U.S.)
- Ointment (U.S.)
Halcinonide
- Cream (U.S. and Canada)
- Ointment (U.S. and Canada)
- Topical solution (U.S. and Canada)
Halobetasol
- Cream (U.S.)
- Ointment (U.S.)
Hydrocortisone butyrate
- Cream (U.S.)
- Ointment (U.S.)
Hydrocortisone probutate
- Cream (Canada)
Hydrocortisone valerate
- Cream (U.S. and Canada)
- Ointment (U.S. and Canada)
Mometasone
- Cream (U.S. and Canada)
- Lotion (U.S. and Canada)
- Ointment (U.S. and Canada)
Prednicarbate
- Cream (U.S.)
Triamcinolone
- Cream (U.S. and Canada)
- Lotion (U.S.)
- Ointment (U.S. and Canada)
- Topical aerosol (U.S.)

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For corticosteroids, the following should be considered:

Allergies?/strong>Tell your doctor if you have ever had any unusual or allergic reaction to corticosteroids. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy?/strong>When used properly, these medicines have not been shown to cause problems in humans. Studies on birth defects have not been done in humans. However, studies in animals have shown that topical corticosteroids, when applied to the skin in large amounts or used for a long time, could cause birth defects.

Breast-feeding?/strong>Topical corticosteroids have not been reported to cause problems in nursing babies when used properly. However, corticosteroids should not be applied to the breasts before nursing.

Children?/strong>Children and teenagers who must use this medicine should be checked often by their doctor since this medicine may be absorbed through the skin and can affect growth or cause other unwanted effects.

Older adults?/strong>Certain side effects may be more likely to occur in elderly patients since the skin of older adults may be naturally thin. These unwanted effects may include tearing of the skin or blood-containing blisters on the skin.

Other medicines?/strong>Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) medicine that is to be applied to the same area of the skin.

Other medical problems?/strong>The presence of other medical problems may affect the use of topical corticosteroids. Make sure you tell your doctor if you have any other medical problems, especially:

Cataracts or

Glaucoma—Corticosteroids may make these medical problems worse, especially when stronger corticosteroids are used in the eye area

Diabetes mellitus (sugar diabetes)—Too much use of corticosteroids may cause a loss of control of diabetes by increasing blood and urine glucose. However, this is not likely to happen when topical corticosteroids are used for a short time

Infection or sores at the place of treatment (unless your doctor also prescribed medicine for the infection) or

Tuberculosis—Corticosteroids may make existing infections worse or cause new infections

Skin conditions that cause thinning of skin with easy bruising—Corticosteroids may make thinning of the skin worse

Proper Use of This Medicine

Be very careful not to get this medicine in your eyes. Wash your hands after using your finger to apply the medicine. If you accidentally get this medicine in your eyes, flush them with water.
Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor.
If your doctor has ordered an occlusive dressing (airtight covering, such as kitchen plastic wrap or a special patch) to be applied over this medicine, make sure you know how to apply it. Since occlusive dressings increase the amount of medicine absorbed through your skin and the possibility of side effects, use them only as directed. If you have any questions about this, check with your doctor.
Do not use on face, groin, or armpits unless directed to do so by your doctor.
For patients using the foam form of this medicine:

This medicine usually comes with patient directions. Read them carefully before using this medicine.

Do not use near heat, near an open flame, or while smoking.

For patients using the topical aerosol form of this medicine:

This medicine usually comes with patient directions. Read them carefully before using this medicine.

It is important to avoid breathing in the vapors from the spray or getting them in your eyes. If you accidentally get this medicine in your eyes, flush them with water.

Do not use near heat, near an open flame, or while smoking.

For patients using flurandrenolide tape:

This medicine usually comes with patient directions. Read them carefully before using this medicine.

Do not use this medicine more often or for a longer time than your doctor ordered. To do so may increase the chance of absorption through the skin and the chance of side effects. In addition, too much use, especially on areas with thinner skin (for example, face, armpits, groin), may result in thinning of the skin and stretch marks or other unwanted effects.
Do not use this medicine for other skin problems without first checking with your doctor. Topical corticosteroids should not be used on many kinds of bacterial, viral, or fungal skin infections.
Dosing?/strong>
The dose of topical corticosteroid will be different for different patients and products. Follow your doctor's orders or the directions on the label.
Missed dose?/strong>
If your doctor has ordered you to use this medicine on a regular schedule and you miss a dose, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and apply it at the next regularly scheduled time.
Storage?/strong>
To store this medicine:

Keep out of the reach of children.

Store away from heat and direct light.

Keep the medicine from freezing.

Do not puncture, break, or burn aerosol containers, even after they are empty.

Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Precautions While Using This Medicine

Check with your doctor if your symptoms do not improve within 1 week or if your condition gets worse.
Avoid using tight-fitting diapers or plastic pants on a child if this medicine is being used on the child's diaper area. Plastic pants or tight-fitting diapers may increase the chance of absorption of the medicine through the skin and the chance of side effects.

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less frequent or rare

Blood-containing blisters on skin; burning and itching of skin; increased skin sensitivity (for some brands of betamethasone lotion); lack of healing of skin condition; loss of top skin layer (for tape dosage forms); numbness in fingers; painful, red or itchy, pus-containing blisters in hair follicles ; raised, dark red, wart-like spots on skin, especially when used on the face; skin infection; thinning of skin with easy bruising

Additional side effects may occur if you use this medicine improperly or for a long time. Check with your doctor if any of the following side effects occur:

Rare

Acne or oily skin; backache; blurring or loss of vision (occurs gradually if certain products have been used near the eye); burning and itching of skin with pinhead-sized red blisters; eye pain (if certain products have been used near the eye); filling or rounding out of the face; increased blood pressure; irregular heartbeat; irregular menstrual periods; irritability; irritation of skin around mouth; loss of appetite; mental depression; muscle cramps, pain, or weakness; nausea; rapid weight gain or loss; reddish purple lines (stretch marks) on arms, face, legs, trunk, or groin; skin color changes; softening of skin; stomach bloating, burning, cramping, or pain; swelling of feet or lower legs; tearing of the skin ; unusual bruising; unusual decrease in sexual desire or ability (in men); unusual increase in hair growth, especially on the face; unusual loss of hair, especially on the scalp; unusual tiredness or weakness; vomiting; weakness of the arms, legs, or trunk (severe); worsening of infections

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

Less frequent or rare--usually mild and transient

Burning, dryness, irritation, itching, or redness of skin; increased redness or scaling of skin sores; skin rash

When the foam, gel, lotion, solution, or aerosol form of this medicine is applied, a mild, temporary stinging may be expected.

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Additional Information

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, topical corticosteroids may be used in certain patients with the following medical conditions:

Phimosis

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