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Anti-Depressants Drugs: Fluoxetin
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| Studies have shown that children and teenagers who take antidepressants ('mood elevators') such as fluoxetine are more likely to think about harming or killing themselves or to plan or try to do so than children who do not take antidepressants.If your child’s doctor has prescribed fluoxetine for your child, you should watch his or her behavior very carefully, especially at the beginning of treatment and any time his or her dose is increased or decreased. Your child may develop serious symptoms very suddenly, so it is important to pay attention to his or her behavior every day. Call your child’s doctor right away if he or she experiences any of these symptoms: new or worsening depression; thinking about harming or killing him- or herself or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling or staying asleep; irritability; aggressive behavior; acting without thinking; severe restlessness; frenzied abnormal excitement, or any other sudden or unusual changes in behavior.Your child’s doctor will want to see your child often while he or she is taking fluoxetine, especially at the beginning of his or her treatment .Your child’s doctor may also want to speak with you or your child by telephone from time to time. Be sure that your child keeps all appointments for office visits or telephone conversations with his or her doctor.Talk to your child’s doctor about the risks of giving fluoxetine to your child. |
Why is this medication prescribed?
Fluoxetine (Prozac) is used to treat depression, obsessive-compulsive disorder (bothersome thoughts that won't go away and the need to perform certain actions over and over), some eating disorders, and panic attacks (sudden, unexpected attacks of extreme fear and worry about these attacks). Fluoxetine (Sarafem) is used to relieve the symptoms of premenstrual dysphoric disorder, including mood swings, irritability, bloating, and breast tenderness. Fluoxetine is in a class of medications called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.
How should this medicine be used?
Fluoxetine (Prozac) comes as a capsule, a tablet, a delayed-release (long-acting) capsule, and a solution (liquid) to take by mouth. Fluoxetine may be taken with or without food. Fluoxetine (Sarafem) comes as a capsule to take by mouth. Fluoxetine (Prozac) capsule, tablet, and liquid are usually taken once a day in the morning or twice a day, in the morning and at noon. Fluoxetine delayed-relayed capsule is usually taken once a week. Fluoxetine (Sarafem) is usually taken once a day, either every day of the month or on certain days of the month. To help you remember to take fluoxetine, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take fluoxetine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Your doctor may start you on a low dose of fluoxetine and gradually increase your dose.
It may take 4 to 5 weeks or longer before you feel the full benefit of fluoxetine. Continue to take fluoxetine even if you feel well. Do not stop taking fluoxetine without talking to your doctor. Your doctor will probably decrease your dose gradually.
Your doctor or pharmacist will give you the manufacturer’s patient information sheet when you begin treatment with fluoxetine. Read the information carefully and ask your doctor or pharmacist if you have any questions.
Other uses for this medicine
Fluoxetine is also sometimes used to treat alcoholism, attention-deficit disorder, borderline personality disorder, sleep disorders, headaches, mental illness, posttraumatic stress disorder, Tourette's syndrome, obesity, sexual problems, and phobias. Talk to your doctor about the possible risks of using this medication for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking fluoxetine,
- tell your doctor and pharmacist if you are allergic to fluoxetine or any other medications.
- do not take fluoxetine if you are taking monoamine oxidase (MAO) inhibitors, including phenelzine (Nardil) and tranylcypromine (Parnate), or have stopped taking them within the past 2 weeks. Do not take fluoxetine with thioridazine (Mellaril).
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: alprazolam (Xanax); anticoagulants ('blood thinners') such as warfarin (Coumadin); antidepressants (mood elevators) such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin), and naproxen (Aleve, Naprosyn); diazepam (Valium); digoxin (Lanoxin); flecainide (Tambocor); insulin or oral medications for diabetes; lithium (Eskalith, Lithobid); medications for anxiety and Parkinson's disease; medications for mental illness such as clozapine (Clozaril), haloperidol (Haldol), and pimozide (Orap); medications for seizures such as carbamazepine (Tegretol) and phenytoin (Dilantin); sedatives; sleeping pills; sumatriptan (Imitrex); tranquilizers; tryptophan; and vinblastine (Velban). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have or have ever had, or anyone in your family has or has ever had, depression, bipolar disorder (mood that changes from depressed to abnormally excited), or mania (frenzied, abnormally excited mood), or you have, or anyone in your family has, thought about or attempted suicide. Also tell your doctor if you have recently had a heart attack and if you have or have ever had diabetes, seizures, or liver or heart disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking fluoxetine, call your doctor.
- you should know that fluoxetine may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
- remember that alcohol can add to the drowsiness caused by this medication.
- you should know that your mental health may change in unexpected ways, especially at the beginning of your treatment and at any time your dose is increased or decreased. These changes may occur at any time if you have depression or other mental illness, whether or not you are taking fluoxetine or any other medication. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling or staying asleep; irritability; aggressive behavior; acting without thinking; severe restlessness; and frenzied, abnormal excitement.Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor when you are unable to seek treatment on your own.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Fluoxetine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- nervousness
- difficulty falling asleep or staying asleep
- upset stomach
- dry mouth
- sore throat
- drowsiness
- weakness
- shaking hands that you cannot control
- loss of appetite
- weight loss
- changes in sex drive or ability
- excessive sweating
Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them or those listed in the IMPORTANT WARNING section, call your doctor immediately:
- skin rash
- hives
- fever
- joint pain
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- difficulty breathing or swallowing
- seeing things or hearing voices that do not exist (hallucinating)
- seizure
Fluoxetine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include:
- unsteadiness
- confusion
- unresponsiveness
- nervousness
- shaking hands that you cannot control
- dizziness
- rapid, irregular, or pounding heartbeat
- seeing things or hearing voices that do not exist (hallucinating)
- fever
- fainting
- coma
What other information should I know?
Keep all appointments with your doctor.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription
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