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Meridia 10mg, Cheap Meridia 10mg, Sibutramine 10mg
May also be referred to as: Reductil, Sibutramine.
This medication is used to reduce excess body weight (obesity). Generic Meridia
Generic Meridia ( Reductil )
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Possible uses of this medication
Meridia is used as an appetite suppressant. It is used in conjunction
with an overall diet plan to reduce weight.
How to take this medication
Take this medication on an empty stomach, once daily, 30-60 minutes before breakfast. The full effect on
weight may require four to six weeks. Do not increase your dose, take it more
frequently or use it for a longer period of time than prescribed because this
drug can be habit-forming. Also, if used for a longer period of time, do not
suddenly stop using this drug without your doctor's approval. Over time, this
drug may not work as well as it did at the beginning. Consult your doctor if
weight increases.
Side Effects
Dry mouth, drowsiness, constipation and difficulty sleeping may occur. If these
effects persist or worsen, notify your doctor promptly.
Precautions
Before using this drug, tell your doctor your entire medical history, including
any allergies (especially drug allergies), liver or kidney disease, high blood
pressure or heart disease, history of stroke or seizures, certain eating
disorders (e.g., anorexia nervosa), glaucoma (narrow angle), or history of
gallstones. Limit alcohol intake, as it may worsen certain side effects of this
medication. It is recommended that women of child-bearing age should use
effective birth control while taking this medication. This drug is not
recommended for use during pregnancy. Consult your doctor before using this
drug. It is not known whether this drug is excreted into breast milk. Because of
the potential risk to the infant, breast-feeding while using this drug is not
recommended. Consult your doctor before breast-feeding. Elderly patients may be
more sensitive to the effects of this drug. Use cautiously.
Drug Interactions
Tell your doctor of all nonprescription and prescription medication you may use,
especially other weight reducing agents (e.g., diethylpropion), drugs that can
raise blood pressure such as decongestants (e.g., pseudoephedrine,
phenylpropanolamine), cough suppressants (e.g., dextromethorphan),
antidepressants (e.g., nefazodone, fluoxetine, paroxetine, sertraline,
fluvoxamine, venlafaxine), lithium, psychiatric medications (e.g., MAO
Inhibitors such as selegiline, moclobemide, furazolidone, phenelzine,
tranylcypromine), drugs for migraines (e.g., dihydroergotamine, sumatriptan),
tryptophan, certain narcotic pain relievers (e.g., meperidine, pentazocine,
fentanyl), ketoconazole, erythromycin, high blood pressure medicine or any drugs
which can cause drowsiness, including certain antihistamines (e.g.,
diphenhydramine), sedatives and anti-seizure drugs. Antihistamines and
decongestants may be found in many nonprescription drugs for cough and cold.
Consult your pharmacist. MAO Inhibitors (see above) and this drug should not be
taken together. If an MAO Inhibitor or this drug is stopped, wait 2 weeks before
starting the other drug.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is near the time of
the next dose, skip the missed dose and resume your usual dosing schedule. Do
not "double- up" the dose to catch up.
Storage
Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away
from light and moisture. Keep this and all medications out of the reach of
children.
Notes
Do not share this medication with others. This medication should be used in
addition to a reduced calorie diet. Blood pressure and pulse may be measured and
laboratory tests performed to monitor side effects.
Professional DESCRIPTION
MERIDIA (sibutramine hydrochloride monohydrate) is an orally administered
agent for the treatment of obesity. Chemically, the active ingredient is a
racemic mixture of the (+) and (-) enantiomers of cyclobutanemethanamine,
1-(4-chlorophenyl)-N,N-dimethyl-a -(2-methylpropyl)-, hydrochloride,
monohydrate, and has an empirical formula of C17H29Cl2NO.
Its molecular weight is 334.33.
The structural formula is shown below:

Sibutramine hydrochloride monohydrate is a white to cream crystalline powder
with a solubility of 2.9 mg/mL in pH 5.2 water. Its octanol:water partition
coefficient is 30.9 at pH 5.0
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