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Paxil (paroxetine chl)
Paxil is a selective serotonin reuptake inhibitor (SSRI) used to treat depression, panic attacks, obsessive compulsive disorders (OCD), social anxiety disorder (SAD) and generalized anxiety disorder. Paxil works by helping to restore the balance of certain natural chemicals in the brain. Paxil?is used to treat depression, panic attacks, obsessive compulsive disorders (OCD), social anxiety disorder (social phobia), and generalized anxiety disorder.
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Paxil
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IMPORTANT
NOTE: The following information is
intended to supplement, not substitute for,
the expertise and judgment of your physician,
pharmacist or other healthcare professional.
It should not be construed to indicate that
use of the drug is safe, appropriate, or effective
for you. Consult your healthcare professional
before using this drug.
PAROXETINE - ORAL
(pair-OX-eh-teen)
COMMON BRAND NAME(S):
Paxil
USES: Paroxetine
is used to treat depression, panic attacks,
obsessive compulsive disorders (OCD), social
anxiety disorder (social phobia), and generalized
anxiety disorder. This paxil works by helping
to restore the balance of certain natural chemicals
in the brain.
OTHER USES:
This paxil has also been used to treat
a severe form of premenstrual syndrome (premenstrual
dysphoric disorder- PMDD), sexual function problems
in men (premature ejaculation), nerve problems
associated with diabetes (diabetic neuropathy),
chronic headaches, or post-traumatic stress
disorder (PTSD).
HOW TO USE:
Take this paxil by mouth usually once daily
in the morning, with or without food; or as
directed by your doctor. The dosage is based
on your medical condition and response to therapy.
It is important to continue taking this paxil
as prescribed even if you feel well. Also, do
not stop taking this paxil without consulting
your doctor. It may take up to several weeks
before the full benefit of this drug takes effect.
SIDE EFFECTS:
Nausea, drowsiness, dizziness, diarrhea, trouble
sleeping, constipation, or dry mouth may occur.
If any of these effects persist or worsen, notify
your doctor promptly. Tell your doctor immediately
if any of these serious SIDE EFFECTS occur:
loss of appetite, unusual or severe mental/mood
changes, increased sweating/flushing, unusual
fatigue, uncontrolled movements (tremor), decreased
interest in sex. Tell your doctor immediately
if any of these unlikely but serious SIDE EFFECTS
occur: blurred vision, changes in sexual ability,
painful and/or prolonged erection, change in
amount of urine. Tell your doctor immediately
if any of these highly unlikely but very serious SIDE EFFECTS occur: fainting, irregular heartbeat,
muscle pain, trouble swallowing, unusual swelling,
seizures, easy bruising or bleeding, tingling
or numbness of the hands/feet. An allergic reaction
to this drug is unlikely, but seek immediate
medical attention if it occurs. Symptoms of
an allergic reaction include: rash, itching,
swelling, severe dizziness, trouble breathing.
If you notice other effects not listed above,
contact your doctor or pharmacist.
PRECAUTIONS : Tell
your doctor your medical history, especially
of: liver problems, kidney problems, seizures,
heart problems, other mental/mood disorders
(e.g., bipolar disorder), thyroid problems,
any allergies. This drug may make you dizzy
or drowsy; use caution engaging in activities
requiring alertness such as driving or using
machinery. Limit alcoholic beverages. Caution
is advised when using this product in the elderly
because they may be more sensitive to the effects
of the drug. This paxil should be used
only when clearly needed during pregnancy. Discuss
the risks and benefits with your doctor. This
drug passes into breast milk. Because of the
potential risk to the infant, breast-feeding
while using this drug is not recommended. Consult
your doctor before breast-feeding.
DRUG INTERACTIONS:
Certain paxils taken with this product
could result in serious, even fatal, DRUG INTERACTIONS.Avoid taking MAO inhibitors (e.g., furazolidone,
isocarboxazid, linezolid, moclobemide, phenelzine,
procarbazine, selegiline, tranylcypromine) within
2 weeks, and avoid taking thioridazine within
5 weeks, before or after treatment with this
paxil. Consult your doctor or pharmacist
for additional information. This drug is not
recommended for use with: weight loss drugs
(e.g., sibutramine, phentermine), thioridazine,
terfenadine, astemizole. Ask your doctor or
pharmacist for more details. Tell your doctor
of all prescription and nonprescription paxil
you may use, especially: other SSRI antidepressants
(e.g., citalopram, fluoxetine), nefazodone,
trazodone, tramadol, venlafaxine, "triptan"
migraine drugs (e.g., sumatriptan, zolmitriptan),
tricyclic antidepressants (e.g., amitriptyline,
nortriptyline), cimetidine, digoxin, flecainide,
propafenone, clozapine, lithium, tryptophan,
"blood thinners" (e.g., warfarin),
theophylline, herbal/natural products (e.g.,
melatonin, ayahuasca, St John's wort). Tell
your doctor if you take any drugs that cause
drowsiness such as: medicine for sleep, sedatives,
tranquilizers, anti- anxiety drugs (e.g., diazepam),
narcotic pain relievers (e.g., codeine), psychiatric
medicines (e.g., phenothiazines such as chlorpromazine),
anti-seizure drugs (e.g., carbamazepine), muscle
relaxants, certain antihistamines (e.g., diphenhydramine).
Report other drugs which affect the heart rhythm
(QTc prolongation), such as: dofetilide, pimozide,
sotalol, quinidine, procainamide, sparfloxacin,
"water pills" (diuretics such as furosemide
or hydrochlorothiazide). Ask your doctor or
pharmacist for more details. Do not start or
stop any medicine without doctor or pharmacist
approval.
OVERDOSE: If OVERDOSEis suspected, contact your local poison
control center or emergency room immediately.
Symptoms If OVERDOSEmay include: irregular
heartbeat, fainting, severe dizziness or lightheadedness.
NOTES : Do not
share this paxil with others. Laboratory
and/or medical tests may be performed to monitor
your progress.
MISSED DOSE :
If you miss a dose, use it as soon as you remember.
If it is near the time of the next dose, skip
the MISSED DOSEand resume your usual dosing
schedule. Do not double the dose to catch up.
STORAGE : Store
at room temperature between 59 and 86 degrees
F (15 and 30 degrees C) away from light and
moisture.
Paroxetine hydrochloride is an odorless, off-white powder, having a melting
point range of 120° to 138°C and a solubility of 5.4 mg/mL in water.
Tablets
Each film-coated tablet contains paroxetine hydrochloride equivalent to
paroxetine as follows: 10 mg-yellow (scored); 20 mg-pink (scored); 30 mg-blue,
40 mg-green. Inactive ingredients consist of dibasic calcium phosphate dihydrate,
hypromellose, magnesium stearate, polyethylene glycols, polysorbate 80, sodium
starch glycolate, titanium dioxide, and 1 or more of the following: D&C Red
No. 30, D&C Yellow No. 10, FD&C Blue No. 2, FD&C Yellow No. 6.
Suspension for Oral Administration
Each 5 mL of orange-colored, orange-flavored liquid contains paroxetine
hydrochloride equivalent to paroxetine, 10 mg. Inactive ingredients consist of
polacrilin potassium, microcrystalline cellulose, propylene glycol, glycerin,
sorbitol, methyl paraben, propyl paraben, sodium citrate dihydrate, citric acid
anhydrate, sodium saccharin, flavorings, FD&C Yellow No. 6, and simethicone
emulsion, USP.
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